Insights on the mechanism of action of immunostimulants in relation to their pharmacological potency. The effects of imidazoquinolines on TLR8

Imidazoquinolines are powerful immunostimulants (IMMS) that function through Toll-like receptors, particularly TLR7 and TLR8. In addition to enhancing the immune response, IMMS also function as antineoplastic drugs and vaccine adjuvants. These small compounds display almost the same molecular struct...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubli-Garfias, Carlos, Vázquez-Ramírez, Ricardo, Trejo-Muñoz, Cynthia, Berber, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459437/
https://www.ncbi.nlm.nih.gov/pubmed/28582454
http://dx.doi.org/10.1371/journal.pone.0178846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459437/
https://www.ncbi.nlm.nih.gov/pubmed/28582454
http://dx.doi.org/10.1371/journal.pone.0178846

Ejemplares similares