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Insights on the mechanism of action of immunostimulants in relation to their pharmacological potency. The effects of imidazoquinolines on TLR8
Imidazoquinolines are powerful immunostimulants (IMMS) that function through Toll-like receptors, particularly TLR7 and TLR8. In addition to enhancing the immune response, IMMS also function as antineoplastic drugs and vaccine adjuvants. These small compounds display almost the same molecular struct...
Autores principales: | Kubli-Garfias, Carlos, Vázquez-Ramírez, Ricardo, Trejo-Muñoz, Cynthia, Berber, Arturo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459437/ https://www.ncbi.nlm.nih.gov/pubmed/28582454 http://dx.doi.org/10.1371/journal.pone.0178846 |
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