Acid sphingomyelinase deficiency enhances myelin repair after acute and chronic demyelination

The cuprizone animal model, also known as the toxic demyelination model, is a well-reproducible model of demyelination- and remyelination in mice, and has been useful in studying important aspect of human demyelinating diseases, including multiple sclerosis. In this study, we investigated the role o...

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Detalles Bibliográficos
Autores principales: Chami, Marwan, Halmer, Ramona, Schnoeder, Laura, Anne Becker, Katrin, Meier, Carola, Fassbender, Klaus, Gulbins, Erich, Walter, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459450/
https://www.ncbi.nlm.nih.gov/pubmed/28582448
http://dx.doi.org/10.1371/journal.pone.0178622