Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia

Glucocorticoids (GCs) and topoisomerase II inhibitors are used to treat acute lymphoblastic leukaemia (ALL) as they induce death in lymphoid cells through the glucocorticoid receptor (GR) and p53 respectively. Mechanisms underlying ALL cell death and the contribution of the bone marrow microenvironm...

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Detalles Bibliográficos
Autores principales: Qattan, Malak Yahia, Bakker, Emyr Yosef, Rajendran, Ramkumar, Chen, Daphne Wei-Chen, Saha, Vaskar, Liu, Jizhong, Zeef, Leo, Schwartz, Jean-Marc, Mutti, Luciano, Demonacos, Constantinos, Krstic-Demonacos, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459454/
https://www.ncbi.nlm.nih.gov/pubmed/28582465
http://dx.doi.org/10.1371/journal.pone.0178606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459454/
https://www.ncbi.nlm.nih.gov/pubmed/28582465
http://dx.doi.org/10.1371/journal.pone.0178606

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