Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations

Understanding the cellular-molecular substrates of heart disease is key to the development of cardiac specific therapies and to the prevention of off-target effects by non-cardiac targeted drugs. One of the primary targets for therapeutic intervention has been the human ether a go-go (hERG) K(+) cha...

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Detalles Bibliográficos
Autores principales: Ocorr, Karen, Zambon, Alexander, Nudell, Yoav, Pineda, Santiago, Diop, Soda, Tang, Min, Akasaka, Takeshi, Taylor, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459509/
https://www.ncbi.nlm.nih.gov/pubmed/28542428
http://dx.doi.org/10.1371/journal.pgen.1006786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459509/
https://www.ncbi.nlm.nih.gov/pubmed/28542428
http://dx.doi.org/10.1371/journal.pgen.1006786

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