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Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast

Experiments in model organisms report abundant genetic interactions underlying biologically important traits, whereas quantitative genetics theory predicts, and data support, that most genetic variance in populations is additive. Here we describe networks of capacitating genetic interactions that co...

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Detalles Bibliográficos
Autores principales: Forsberg, Simon K. G., Bloom, Joshua S., Sadhu, Meru J., Kruglyak, Leonid, Carlborg, Örjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459553/
https://www.ncbi.nlm.nih.gov/pubmed/28250458
http://dx.doi.org/10.1038/ng.3800