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The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition
Antibodies are critical components of the human adaptive immune system, providing versatile scaffolds to display diverse antigen-binding surfaces. Nevertheless, most antibodies have similar architectures, with the variable immunoglobulin domains of the heavy and light chain each providing three hype...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459573/ https://www.ncbi.nlm.nih.gov/pubmed/28527239 http://dx.doi.org/10.7554/eLife.27311 |