Cargando…
The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition
Antibodies are critical components of the human adaptive immune system, providing versatile scaffolds to display diverse antigen-binding surfaces. Nevertheless, most antibodies have similar architectures, with the variable immunoglobulin domains of the heavy and light chain each providing three hype...
Autores principales: | Hsieh, Fu-Lien, Higgins, Matthew K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459573/ https://www.ncbi.nlm.nih.gov/pubmed/28527239 http://dx.doi.org/10.7554/eLife.27311 |
Ejemplares similares
-
The Structural Basis of Antibody-Antigen Recognition
por: Sela-Culang, Inbal, et al.
Publicado: (2013) -
LAIR-1 Limits Neutrophilic Airway Inflammation
por: Kumawat, Kuldeep, et al.
Publicado: (2019) -
Public antibodies to malaria antigens generated by two LAIR1
insertion modalities
por: Pieper, Kathrin, et al.
Publicado: (2017) -
Blocking LAIR1 signaling in immune cells inhibits tumor development
por: Xie, Jingjing, et al.
Publicado: (2022) -
A LAIR-1 insertion generates broadly reactive antibodies against malaria variant antigens
por: Tan, Joshua, et al.
Publicado: (2015)