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Functionally diverse human T cells recognize non-microbial antigens presented by MR1

MHC class I-related molecule MR1 presents riboflavin- and folate-related metabolites to mucosal-associated invariant T cells, but it is unknown whether MR1 can present alternative antigens to other T cell lineages. In healthy individuals we identified MR1-restricted T cells (named MR1T cells) displa...

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Detalles Bibliográficos
Autores principales: Lepore, Marco, Kalinichenko, Artem, Calogero, Salvatore, Kumar, Pavanish, Paleja, Bhairav, Schmaler, Mathias, Narang, Vipin, Zolezzi, Francesca, Poidinger, Michael, Mori, Lucia, De Libero, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459576/
https://www.ncbi.nlm.nih.gov/pubmed/28518056
http://dx.doi.org/10.7554/eLife.24476