Single-cell protein-mRNA correlation analysis enabled by multiplexed dual-analyte co-detection

We have investigated the correlation between proteins and mRNAs in single cells employing an integrated workflow for dual-analyte co-detection. This is achieved by combining the oligo extension reaction (OER), which converts protein levels to DNA levels, with reverse transcription for mRNA detection...

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Detalles Bibliográficos
Autores principales: Gong, Haibiao, Wang, Xiaohui, Liu, Benjamin, Boutet, Stephane, Holcomb, Ilona, Dakshinamoorthy, Gajalakshmi, Ooi, Aik, Sanada, Chad, Sun, Gang, Ramakrishnan, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459813/
https://www.ncbi.nlm.nih.gov/pubmed/28584233
http://dx.doi.org/10.1038/s41598-017-03057-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459813/
https://www.ncbi.nlm.nih.gov/pubmed/28584233
http://dx.doi.org/10.1038/s41598-017-03057-5

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