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Single-cell protein-mRNA correlation analysis enabled by multiplexed dual-analyte co-detection
We have investigated the correlation between proteins and mRNAs in single cells employing an integrated workflow for dual-analyte co-detection. This is achieved by combining the oligo extension reaction (OER), which converts protein levels to DNA levels, with reverse transcription for mRNA detection...
Autores principales: | Gong, Haibiao, Wang, Xiaohui, Liu, Benjamin, Boutet, Stephane, Holcomb, Ilona, Dakshinamoorthy, Gajalakshmi, Ooi, Aik, Sanada, Chad, Sun, Gang, Ramakrishnan, Ramesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459813/ https://www.ncbi.nlm.nih.gov/pubmed/28584233 http://dx.doi.org/10.1038/s41598-017-03057-5 |
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