Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats

Chronic treatment with second-generation antipsychotic drugs (SGAs) has been associated with an increased risk of metabolic syndrome. To evaluate the longitudinal changes in glucose-lipid homeostasis after SGA use, we studied the time-dependent effects of olanzapine (OLZ) (3 mg/kg, b.i.d.) or clozap...

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Detalles Bibliográficos
Autores principales: Liu, Xuemei, Wu, Zhixiang, Lian, Jiamei, Hu, Chang-Hua, Huang, Xu-Feng, Deng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459828/
https://www.ncbi.nlm.nih.gov/pubmed/28584269
http://dx.doi.org/10.1038/s41598-017-02884-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459828/
https://www.ncbi.nlm.nih.gov/pubmed/28584269
http://dx.doi.org/10.1038/s41598-017-02884-w

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