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Synthetic surfactant- and cross-linker-free preparation of highly stable lipid-polymer hybrid nanoparticles as potential oral delivery vehicles

The toxicity associated with concentrated synthetic surfactants and the poor stability at gastrointestinal condition are two major constraints for practical applications of solid lipid nanoparticles (SLN) as oral delivery vehicles. In this study, a synthetic surfactant-free and cross-linker-free met...

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Detalles Bibliográficos
Autores principales: Wang, Taoran, Xue, Jingyi, Hu, Qiaobin, Zhou, Mingyong, Chang, Chao, Luo, Yangchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459848/
https://www.ncbi.nlm.nih.gov/pubmed/28584240
http://dx.doi.org/10.1038/s41598-017-02867-x