Mild Traumatic Brain Injury Evokes Pyramidal Neuron Axon Initial Segment Plasticity and Diffuse Presynaptic Inhibitory Terminal Loss

The axon initial segment (AIS) is the site of action potential (AP) initiation, thus a crucial regulator of neuronal activity. In excitatory pyramidal neurons, the high density of voltage-gated sodium channels (NaV1.6) at the distal AIS regulates AP initiation. A surrogate AIS marker, ankyrin-G (ank...

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Detalles Bibliográficos
Autores principales: Vascak, Michal, Sun, Jianli, Baer, Matthew, Jacobs, Kimberle M., Povlishock, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459898/
https://www.ncbi.nlm.nih.gov/pubmed/28634442
http://dx.doi.org/10.3389/fncel.2017.00157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459898/
https://www.ncbi.nlm.nih.gov/pubmed/28634442
http://dx.doi.org/10.3389/fncel.2017.00157

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