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Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent

Copper diethyldithiocarbamate (Cu(DDC)(2)) is the active anticancer agent generated when disulfiram (DSF) is provided in the presence of copper. To date, research directed toward repurposing DSF as an anticancer drug has focused on administration of DSF and copper in combination, efforts that have p...

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Detalles Bibliográficos
Autores principales: Wehbe, Mohamed, Anantha, Malathi, Shi, Minghan, Leung, Ada Wai-yin, Dragowska, Wieslawa H, Sanche, Léon, Bally, Marcel B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459956/
https://www.ncbi.nlm.nih.gov/pubmed/28615941
http://dx.doi.org/10.2147/IJN.S137347