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Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent
Copper diethyldithiocarbamate (Cu(DDC)(2)) is the active anticancer agent generated when disulfiram (DSF) is provided in the presence of copper. To date, research directed toward repurposing DSF as an anticancer drug has focused on administration of DSF and copper in combination, efforts that have p...
Autores principales: | Wehbe, Mohamed, Anantha, Malathi, Shi, Minghan, Leung, Ada Wai-yin, Dragowska, Wieslawa H, Sanche, Léon, Bally, Marcel B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459956/ https://www.ncbi.nlm.nih.gov/pubmed/28615941 http://dx.doi.org/10.2147/IJN.S137347 |
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