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Glucose represses dendritic cell-induced T cell responses

Glucose and glycolysis are important for the proinflammatory functions of many immune cells, and depletion of glucose in pathological microenvironments is associated with defective immune responses. Here we show a contrasting function for glucose in dendritic cells (DCs), as glucose represses the pr...

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Detalles Bibliográficos
Autores principales: Lawless, Simon J., Kedia-Mehta, Nidhi, Walls, Jessica F., McGarrigle, Ryan, Convery, Orla, Sinclair, Linda V., Navarro, Maria N., Murray, James, Finlay, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459989/
https://www.ncbi.nlm.nih.gov/pubmed/28555668
http://dx.doi.org/10.1038/ncomms15620