Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

The structure and function of spines and excitatory synapses are under the dynamic control of multiple signalling networks. Although tyrosine phosphorylation is involved, its regulation and importance are not well understood. Here we study the role of Pyk2, a non-receptor calcium-dependent protein-t...

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Detalles Bibliográficos
Autores principales: Giralt, Albert, Brito, Veronica, Chevy, Quentin, Simonnet, Clémence, Otsu, Yo, Cifuentes-Díaz, Carmen, de Pins, Benoit, Coura, Renata, Alberch, Jordi, Ginés, Sílvia, Poncer, Jean-Christophe, Girault, Jean-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459995/
https://www.ncbi.nlm.nih.gov/pubmed/28555636
http://dx.doi.org/10.1038/ncomms15592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459995/
https://www.ncbi.nlm.nih.gov/pubmed/28555636
http://dx.doi.org/10.1038/ncomms15592

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