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Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model
The structure and function of spines and excitatory synapses are under the dynamic control of multiple signalling networks. Although tyrosine phosphorylation is involved, its regulation and importance are not well understood. Here we study the role of Pyk2, a non-receptor calcium-dependent protein-t...
Autores principales: | Giralt, Albert, Brito, Veronica, Chevy, Quentin, Simonnet, Clémence, Otsu, Yo, Cifuentes-Díaz, Carmen, de Pins, Benoit, Coura, Renata, Alberch, Jordi, Ginés, Sílvia, Poncer, Jean-Christophe, Girault, Jean-Antoine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5459995/ https://www.ncbi.nlm.nih.gov/pubmed/28555636 http://dx.doi.org/10.1038/ncomms15592 |
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