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Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

DNA nanostructures have evoked great interest as potential therapeutics and diagnostics due to ease and robustness of programming their shapes, site-specific functionalizations and responsive behaviours. However, their utility in biological fluids can be compromised through denaturation induced by p...

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Detalles Bibliográficos
Autores principales: Ponnuswamy, Nandhini, Bastings, Maartje M. C., Nathwani, Bhavik, Ryu, Ju Hee, Chou, Leo Y. T., Vinther, Mathias, Li, Weiwei Aileen, Anastassacos, Frances M., Mooney, David J., Shih, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460023/
https://www.ncbi.nlm.nih.gov/pubmed/28561045
http://dx.doi.org/10.1038/ncomms15654