Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Stromal-derived intratumoural heterogeneity (ITH) has been shown to undermine molecular stratification of patients into appropriate prognostic/predictive subgroups. Here, using several clinically relevant colorectal cancer (CRC) gene expression signatures, we assessed the susceptibility of these sig...

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Detalles Bibliográficos
Autores principales: Dunne, Philip D., Alderdice, Matthew, O'Reilly, Paul G., Roddy, Aideen C., McCorry, Amy M. B., Richman, Susan, Maughan, Tim, McDade, Simon S., Johnston, Patrick G., Longley, Daniel B., Kay, Elaine, McArt, Darragh G., Lawler, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460026/
https://www.ncbi.nlm.nih.gov/pubmed/28561046
http://dx.doi.org/10.1038/ncomms15657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460026/
https://www.ncbi.nlm.nih.gov/pubmed/28561046
http://dx.doi.org/10.1038/ncomms15657

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