HSPs drive dichotomous T-cell immune responses via DNA methylome remodelling in antigen presenting cells

Immune responses primed by endogenous heat shock proteins, specifically gp96, can be varied, and mechanisms controlling these responses have not been defined. Immunization with low doses of gp96 primes T helper type 1 (Th1) immune responses, whereas high-dose immunization primes responses characteri...

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Detalles Bibliográficos
Autores principales: Kinner-Bibeau, Lauren B., Sedlacek, Abigail L., Messmer, Michelle N., Watkins, Simon C., Binder, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460028/
https://www.ncbi.nlm.nih.gov/pubmed/28561043
http://dx.doi.org/10.1038/ncomms15648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460028/
https://www.ncbi.nlm.nih.gov/pubmed/28561043
http://dx.doi.org/10.1038/ncomms15648

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