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Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing

Faithful chromosome segregation during mitosis requires that the kinetochores of all sister chromatids become stably connected to microtubules derived from opposite spindle poles. How stable chromosome bi-orientation is accomplished and coordinated with anaphase onset remains incompletely understood...

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Detalles Bibliográficos
Autores principales: Hengeveld, Rutger C. C., Vromans, Martijn J. M., Vleugel, Mathijs, Hadders, Michael A., Lens, Susanne M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460030/
https://www.ncbi.nlm.nih.gov/pubmed/28561035
http://dx.doi.org/10.1038/ncomms15542