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Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis

The mechanism underlying bone impairment in patients with diabetes mellitus, a metabolic disorder characterized by chronic hyperglycaemia and dysregulation in metabolism, is unclear. Here we show the difference in the metabolomics of bone marrow stromal cells (BMSCs) derived from hyperglycaemic (typ...

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Detalles Bibliográficos
Autores principales: Guo, Yuqi, Xie, Chengzhi, Li, Xiyan, Yang, Jian, Yu, Tao, Zhang, Ruohan, Zhang, Tianqing, Saxena, Deepak, Snyder, Michael, Wu, Yingjie, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460032/
https://www.ncbi.nlm.nih.gov/pubmed/28561074
http://dx.doi.org/10.1038/ncomms15621