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A minor alternative transcript of the fumarylacetoacetate hydrolase gene produces a protein despite being likely subjected to nonsense-mediated mRNA decay

BACKGROUND: Coupling of alternative splicing with nonsense-mediated mRNA decay (NMD) may regulate gene expression. We report here the identification of a nonsense alternative transcript of the fumarylacetoacetate hydrolase (fah) gene, which produces a protein despite the fact that it is subject to N...

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Detalles Bibliográficos
Autores principales: Dreumont, Natacha, Maresca, Antonella, Boisclair-Lachance, Jean-François, Bergeron, Anne, Tanguay, Robert M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546004/
https://www.ncbi.nlm.nih.gov/pubmed/15638932
http://dx.doi.org/10.1186/1471-2199-6-1