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Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models

Although aberrations of intracellular vesicle transport systems towards lysosomes including autophagy and endocytosis are involved in the onset and progression of acute pancreatitis, the molecular mechanisms underlying such aberrations remain unclear. The pathways of autophagy and endocytosis are cl...

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Detalles Bibliográficos
Autores principales: Takahashi, Kenichi, Mashima, Hirosato, Miura, Kouichi, Maeda, Daichi, Goto, Akiteru, Goto, Takashi, Sun-Wada, Ge-Hong, Wada, Yoh, Ohnishi, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460112/
https://www.ncbi.nlm.nih.gov/pubmed/28588238
http://dx.doi.org/10.1038/s41598-017-02988-3