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MDM2 negatively regulates the human telomerase RNA gene promoter

BACKGROUND: We have previously demonstrated that NF-Y and Sp1 interact with the human telomerase RNA (hTR) promoter and play a central role in its regulation. We have also shown that pRB activates the hTR promoter, but the mechanism of pRb directed activation is unknown. It has recently been reporte...

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Detalles Bibliográficos
Autores principales: Zhao, Jiangqin, Bilsland, Alan, Jackson, Katrina, Keith, W Nicol
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546012/
https://www.ncbi.nlm.nih.gov/pubmed/15656906
http://dx.doi.org/10.1186/1471-2407-5-6