An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors

Collective cell migration is a common phenotype in epithelial cancers, which is associated with tumor cell metastasis and poor patient survival. However, the interplay between physiologically relevant pro-migratory stimuli and the underlying mechanical cell–cell interactions are poorly understood. W...

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Detalles Bibliográficos
Autores principales: Stichel, Damian, Middleton, Alistair M., Müller, Benedikt F., Depner, Sofia, Klingmüller, Ursula, Breuhahn, Kai, Matthäus, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460121/
https://www.ncbi.nlm.nih.gov/pubmed/28649432
http://dx.doi.org/10.1038/s41540-017-0006-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460121/
https://www.ncbi.nlm.nih.gov/pubmed/28649432
http://dx.doi.org/10.1038/s41540-017-0006-3

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