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An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors
Collective cell migration is a common phenotype in epithelial cancers, which is associated with tumor cell metastasis and poor patient survival. However, the interplay between physiologically relevant pro-migratory stimuli and the underlying mechanical cell–cell interactions are poorly understood. W...
Autores principales: | Stichel, Damian, Middleton, Alistair M., Müller, Benedikt F., Depner, Sofia, Klingmüller, Ursula, Breuhahn, Kai, Matthäus, Franziska |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460121/ https://www.ncbi.nlm.nih.gov/pubmed/28649432 http://dx.doi.org/10.1038/s41540-017-0006-3 |
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