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Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity

MCM7, a subunit of mini-chromosome maintenance proteins (MCM) complex, plays an important role in initiating DNA replication during the G1 phase and extending DNA strands during the S phase. Here, we demonstrated that MCM7 is not only sustained but maintains association with chromatin during M phase...

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Detalles Bibliográficos
Autores principales: Zheng, Dianpeng, Ye, Sichao, Wang, Xiuyun, Zhang, Yongjun, Yan, Daoyu, Cai, Xiangsheng, Gao, Weihong, Shan, Hongbo, Gao, Yang, Chen, Juanjuan, Hu, Zhiming, Li, Hongwei, Li, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460140/
https://www.ncbi.nlm.nih.gov/pubmed/28588300
http://dx.doi.org/10.1038/s41598-017-03148-3