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Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity
MCM7, a subunit of mini-chromosome maintenance proteins (MCM) complex, plays an important role in initiating DNA replication during the G1 phase and extending DNA strands during the S phase. Here, we demonstrated that MCM7 is not only sustained but maintains association with chromatin during M phase...
Autores principales: | Zheng, Dianpeng, Ye, Sichao, Wang, Xiuyun, Zhang, Yongjun, Yan, Daoyu, Cai, Xiangsheng, Gao, Weihong, Shan, Hongbo, Gao, Yang, Chen, Juanjuan, Hu, Zhiming, Li, Hongwei, Li, Jinlong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460140/ https://www.ncbi.nlm.nih.gov/pubmed/28588300 http://dx.doi.org/10.1038/s41598-017-03148-3 |
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