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Capping Enzyme mRNA-cap/RNGTT Regulates Hedgehog Pathway Activity by Antagonizing Protein Kinase A

Hedgehog (Hh) signaling plays a pivotal role in animal development and its deregulation in humans causes birth defects and several types of cancer. Protein Kinase A (PKA) modulates Hh signaling activity through phosphorylating the transcription factor Cubitus interruptus (Ci) and G protein coupled r...

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Detalles Bibliográficos
Autores principales: Chen, Ping, Zhou, Zizhang, Yao, Xia, Pang, Shu, Liu, Meijing, Jiang, Weirong, Jiang, Jin, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460166/
https://www.ncbi.nlm.nih.gov/pubmed/28588207
http://dx.doi.org/10.1038/s41598-017-03165-2