Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition

Candida albicans is an opportunistic fungal pathogen colonizing the oral cavity. C. albicans secreted aspartic protease Sap6 is important for virulence during oral candidiasis since it degrades host tissues to release nutrients and essential transition metals. We found that zinc specifically increas...

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Detalles Bibliográficos
Autores principales: Kumar, Rohitashw, Breindel, Christine, Saraswat, Darpan, Cullen, Paul J., Edgerton, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460171/
https://www.ncbi.nlm.nih.gov/pubmed/28588252
http://dx.doi.org/10.1038/s41598-017-03082-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460171/
https://www.ncbi.nlm.nih.gov/pubmed/28588252
http://dx.doi.org/10.1038/s41598-017-03082-4

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