Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice

We previously showed that Irisin, a myokine released from skeletal muscle after physical exercise, plays a central role in the control of bone mass. Here we report that treatment with recombinant Irisin prevented bone loss in hind-limb suspended mice when administered during suspension (preventive p...

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Detalles Bibliográficos
Autores principales: Colaianni, Graziana, Mongelli, Teresa, Cuscito, Concetta, Pignataro, Paolo, Lippo, Luciana, Spiro, Giovanna, Notarnicola, Angela, Severi, Ilenia, Passeri, Giovanni, Mori, Giorgio, Brunetti, Giacomina, Moretti, Biagio, Tarantino, Umberto, Colucci, Silvia C., Reseland, Janne E., Vettor, Roberto, Cinti, Saverio, Grano, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460172/
https://www.ncbi.nlm.nih.gov/pubmed/28588307
http://dx.doi.org/10.1038/s41598-017-02557-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460172/
https://www.ncbi.nlm.nih.gov/pubmed/28588307
http://dx.doi.org/10.1038/s41598-017-02557-8

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