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Structural Modeling of Chromatin Integrates Genome Features and Reveals Chromosome Folding Principle
How chromosomes fold into 3D structures and how genome functions are affected or even controlled by their spatial organization remain challenging questions. Hi-C experiment has provided important structural insights for chromosome, and Hi-C data are used here to construct the 3D chromatin structure...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460185/ https://www.ncbi.nlm.nih.gov/pubmed/28588240 http://dx.doi.org/10.1038/s41598-017-02923-6 |