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Structural Modeling of Chromatin Integrates Genome Features and Reveals Chromosome Folding Principle

How chromosomes fold into 3D structures and how genome functions are affected or even controlled by their spatial organization remain challenging questions. Hi-C experiment has provided important structural insights for chromosome, and Hi-C data are used here to construct the 3D chromatin structure...

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Detalles Bibliográficos
Autores principales: Xie, Wen Jun, Meng, Luming, Liu, Sirui, Zhang, Ling, Cai, Xiaoxia, Gao, Yi Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460185/
https://www.ncbi.nlm.nih.gov/pubmed/28588240
http://dx.doi.org/10.1038/s41598-017-02923-6