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Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease

Iron accumulates gradually in the ageing brain. In Parkinson’s disease, iron deposition within the substantia nigra is further increased, contributing to a heightened pro-oxidant environment in dopaminergic neurons. We hypothesise that individuals in high-income countries, where cereals and infant f...

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Detalles Bibliográficos
Autores principales: Hare, Dominic J, Cardoso, Bárbara Rita, Raven, Erika P, Double, Kay L, Finkelstein, David I, Szymlek-Gay, Ewa A, Biggs, Beverley-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460187/
https://www.ncbi.nlm.nih.gov/pubmed/28649601
http://dx.doi.org/10.1038/s41531-016-0004-y