Cargando…

Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease

Iron accumulates gradually in the ageing brain. In Parkinson’s disease, iron deposition within the substantia nigra is further increased, contributing to a heightened pro-oxidant environment in dopaminergic neurons. We hypothesise that individuals in high-income countries, where cereals and infant f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hare, Dominic J, Cardoso, Bárbara Rita, Raven, Erika P, Double, Kay L, Finkelstein, David I, Szymlek-Gay, Ewa A, Biggs, Beverley-Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460187/ https://www.ncbi.nlm.nih.gov/pubmed/28649601 http://dx.doi.org/10.1038/s41531-016-0004-y

Ejemplares similares

Health outcomes of iron supplementation and/or food fortification in iron-replete children aged 4–24 months: protocol for a systematic review and meta-analysis
por: Hare, Dominic J., et al.
Publicado: (2019)

A brief history of brain iron accumulation in Parkinson disease and related disorders
por: Foley, Paul B., et al.
Publicado: (2022)

Oxidative stress in the aging substantia nigra and the etiology of Parkinson's disease
por: Trist, Benjamin G., et al.
Publicado: (2019)

Associations between Dietary Iron and Zinc Intakes, and between Biochemical Iron and Zinc Status in Women
por: Lim, Karen, et al.
Publicado: (2015)

Iron Nutrition of Pre-Schoolers in High-Income Countries: A Review
por: Atkins, Linda A., et al.
Publicado: (2023)

Hepcidin is a Better Predictor of Iron Stores in Premenopausal Women than Blood Loss or Dietary Intake
por: Lim, Karen H. C., et al.
Publicado: (2016)

New perspectives in iron chelation therapy for the treatment of Parkinson’s disease
por: Nuñez, Marco T., et al.
Publicado: (2019)

Iron and Zinc Nutrition in the Economically-Developed World: A Review
por: Lim, Karen H. C., et al.
Publicado: (2013)

Limited therapeutic potential of astrocyte elevated gene-1 transduction in an animal model of Parkinson's disease
por: Leem, Eunju, et al.
Publicado: (2020)

To the Gut Microbiome and Beyond: The Brain-First or Body-First Hypothesis in Parkinson’s Disease
por: Nuzum, Nathan D., et al.
Publicado: (2022)

Insulin resistance in the liver: Deficiency or excess of insulin?
por: Bazotte, Roberto B, et al.
Publicado: (2014)

Effects of Excess Iron on the Retina: Insights From Clinical Cases and Animal Models of Iron Disorders
por: Shahandeh, Ali, et al.
Publicado: (2022)

Mitochondrial-Derived Vesicles as Candidate Biomarkers in Parkinson’s Disease: Rationale, Design and Methods of the EXosomes in PArkiNson Disease (EXPAND) Study
por: Picca, Anna, et al.
Publicado: (2019)

What comes first, misshape or dysfunction? The view from metabolic excess
por: Galloway, Chad A., et al.
Publicado: (2012)

Mobile Phone App Aimed at Improving Iron Intake and Bioavailability in Premenopausal Women: A Qualitative Evaluation
por: Mann, Davina, et al.
Publicado: (2015)

Kidney‐Derived c‐Kit(+) Cells Possess Regenerative Potential
por: Gomes, Samirah A., et al.
Publicado: (2018)

Increasing Iron and Zinc in Pre-Menopausal Women and Its Effects on Mood and Cognition: A Systematic Review
por: Lomagno, Karla A., et al.
Publicado: (2014)

Too Much, Too Mild, Too Early: Diagnosing the Excessive Expansion of Diagnoses
por: Hofmann, Bjørn
Publicado: (2022)

Are Clinicians Contributing to Excess African American COVID-19 Deaths? Unbeknownst to Them, They May Be
por: Milam, Adam J., et al.
Publicado: (2020)

Cancer survivorship, excess body fatness and weight-loss intervention—where are we in 2020?
por: Anderson, Annie S., et al.
Publicado: (2020)

Gastrointestinal iron excretion and reversal of iron excess in a mouse model of inherited iron excess
por: Mercadante, Courtney J., et al.
Publicado: (2019)

Kinetic Modeling of pH-Dependent Oxidation of Dopamine by Iron and Its Relevance to Parkinson's Disease
por: Sun, Yingying, et al.
Publicado: (2018)

Iron chelators or therapeutic modulators of iron overload: Are we anywhere near ideal one?
por: Ghosh, Kanjaksha, et al.
Publicado: (2018)

COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside
por: Sulzer, David, et al.
Publicado: (2020)

Lead and Neuroprotection by Iron in ADHD
por: Konofal, Eric, et al.
Publicado: (2007)

Majorana gets an iron twist
por: Kong, Lingyuan, et al.
Publicado: (2019)

Beverage Consumption among U.S. Children Aged 0–24 Months: National Health and Nutrition Examination Survey (NHANES)
por: Grimes, Carley A., et al.
Publicado: (2017)

Administration of ferrous sulfate drops has significant effects on the gut microbiota of iron-sufficient infants: a randomised controlled study
por: Simonyté Sjödin, Kotryna, et al.
Publicado: (2019)

Cell Therapies for Parkinson's Disease
por: Irion, Stefan
Publicado: (2019)

Mitochondria in the context of Parkinson's disease
por: Villacé, Patricia, et al.
Publicado: (2017)

Falling upward with Parkinson’s disease
por: Buetow, Stephen A., et al.
Publicado: (2017)

Role of Iron in Aging Related Diseases
por: Chen, William J., et al.
Publicado: (2022)

Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic
por: Trist, Benjamin G., et al.
Publicado: (2020)

Clinical Characteristics, Iron Metabolism and Neuroinflammation: New Insight into Excessive Daytime Sleepiness in Parkinson’s Disease
por: Hu, Yang, et al.
Publicado: (2021)

Energy excess is the main cause of accelerated aging of mammals
por: Biliński, Tomasz, et al.
Publicado: (2015)

Genetic Analysis of Pathways to Parkinson Disease
por: Hardy, John
Publicado: (2010)

Parkinson’s disease-associated melanin steal
por: Hinz, Marty, et al.
Publicado: (2014)

Parkinson’s disease: carbidopa, nausea, and dyskinesia
por: Hinz, Marty, et al.
Publicado: (2014)

Efficacy of cognitive rehabilitation in Parkinson's disease
por: Díez-Cirarda, María, et al.
Publicado: (2018)

The paradigm of protein acetylation in Parkinson’s disease
por: Yakhine-Diop, Sokhna M.S., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_q9nnof1s8br1lvuipnssqp0db9