A novel network regularized matrix decomposition method to detect mutated cancer genes in tumour samples with inter-patient heterogeneity

Inter-patient heterogeneity is a major challenge for mutated cancer genes detection which is crucial to advance cancer diagnostics and therapeutics. To detect mutated cancer genes in heterogeneous tumour samples, a prominent strategy is to determine whether the genes are recurrently mutated in their...

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Detalles Bibliográficos
Autores principales: Xi, Jianing, Li, Ao, Wang, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460199/
https://www.ncbi.nlm.nih.gov/pubmed/28588243
http://dx.doi.org/10.1038/s41598-017-03141-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460199/
https://www.ncbi.nlm.nih.gov/pubmed/28588243
http://dx.doi.org/10.1038/s41598-017-03141-w

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