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A novel network regularized matrix decomposition method to detect mutated cancer genes in tumour samples with inter-patient heterogeneity
Inter-patient heterogeneity is a major challenge for mutated cancer genes detection which is crucial to advance cancer diagnostics and therapeutics. To detect mutated cancer genes in heterogeneous tumour samples, a prominent strategy is to determine whether the genes are recurrently mutated in their...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460199/ https://www.ncbi.nlm.nih.gov/pubmed/28588243 http://dx.doi.org/10.1038/s41598-017-03141-w |