In-situ freeze-drying - forming amorphous solids directly within capsules: An investigation of dissolution enhancement for a poorly soluble drug

Conversion into the amorphous form enhances the dissolution of poorly soluble drugs, however the barrier to market for medicines containing an amorphous drug is poor stability. The aim was to produce the amorphous form of a drug within a capsule, without thermal or mechanical stress during manufactu...

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Detalles Bibliográficos
Autores principales: Alqurshi, Abdulmalik, Chan, K. L. Andrew., Royall, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460206/
https://www.ncbi.nlm.nih.gov/pubmed/28588206
http://dx.doi.org/10.1038/s41598-017-02676-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460206/
https://www.ncbi.nlm.nih.gov/pubmed/28588206
http://dx.doi.org/10.1038/s41598-017-02676-2

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