Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease

5-methylcytosine and the oxidation product 5-hydroxymethylcytosine are two prominent epigenetic variants of the cytosine base in nuclear DNA of mammalian brains. We measured levels of 5-methylcytosine and 5-hydroxymethylcytosine by enzyme-linked immunosorbent assay in DNA from post-mortem cerebella...

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Detalles Bibliográficos
Autores principales: Stöger, Reinhard, Scaife, Paula J., Shephard, Freya, Chakrabarti, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460211/
https://www.ncbi.nlm.nih.gov/pubmed/28649606
http://dx.doi.org/10.1038/s41531-017-0007-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460211/
https://www.ncbi.nlm.nih.gov/pubmed/28649606
http://dx.doi.org/10.1038/s41531-017-0007-3

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