Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult stem cells

Growing evidence suggests that many diseases of aging, including diseases associated with robust changes and adipose deports, may be caused by resident adult stem cell exhaustion due to the process called cellular senescence. Understanding how microRNA pathways can regulate cellular senescence is cr...

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Detalles Bibliográficos
Autores principales: Lopez, Mary F., Niu, Ping, Wang, Lu, Vogelsang, Maryann, Gaur, Meenakshi, Krastins, Bryan, Zhao, Yueqiang, Smagul, Aibek, Nussupbekova, Aliya, Akanov, Aikan A., Jordan, I. King, Lunyak, Victoria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460214/
https://www.ncbi.nlm.nih.gov/pubmed/28649425
http://dx.doi.org/10.1038/s41514-017-0006-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460214/
https://www.ncbi.nlm.nih.gov/pubmed/28649425
http://dx.doi.org/10.1038/s41514-017-0006-y

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