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PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer
Pyruvate kinase M2 (PKM2) is a key kinase of glycolysis and is characteristic of all proliferating cells. The role of PKM2 in gastric cancer (GC) is still ambiguous and yet to be determined. To better understand the role of PKM2 in both the migration and invasion of GC, we measured the expression of...
| Auteurs principaux: | , , , , , , , |
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| Format: | Online Article Texte |
| Langue: | English |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460252/ https://www.ncbi.nlm.nih.gov/pubmed/28588255 http://dx.doi.org/10.1038/s41598-017-03031-1 |