PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer

Pyruvate kinase M2 (PKM2) is a key kinase of glycolysis and is characteristic of all proliferating cells. The role of PKM2 in gastric cancer (GC) is still ambiguous and yet to be determined. To better understand the role of PKM2 in both the migration and invasion of GC, we measured the expression of...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Jiang, Jinling, Ji, Jun, Cai, Qu, Chen, Xuehua, Yu, Yingyan, Zhu, Zhenggang, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460252/
https://www.ncbi.nlm.nih.gov/pubmed/28588255
http://dx.doi.org/10.1038/s41598-017-03031-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460252/
https://www.ncbi.nlm.nih.gov/pubmed/28588255
http://dx.doi.org/10.1038/s41598-017-03031-1

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