PCDH18 is frequently inactivated by promoter methylation in colorectal cancer

Protocadherin18 (PCDH18) was found to be preferentially methylated and inactivated in colorectal cancer (CRC) using bioinformatics tools. However, its biologic role in tumorgenesis remains unclear. Herein, we aimed to elucidate its epigenetic regulation and biological functions in CRC. The methylati...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Tang, Weiwei, Su, Guoqiang, Cai, Mingquan, An, Han-Xiang, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460281/
https://www.ncbi.nlm.nih.gov/pubmed/28588296
http://dx.doi.org/10.1038/s41598-017-03133-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460281/
https://www.ncbi.nlm.nih.gov/pubmed/28588296
http://dx.doi.org/10.1038/s41598-017-03133-w

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