Cargando…

Low frequency of NS5A relevant resistance-associated substitutions to Elbasvir among hepatitis C virus genotype 1a in Spain: a cross-sectional study

Relevant resistance-associated substitutions (RASs) to elbasvir, the new HCV NS5A inhibitor, may limit its efficacy and lead to virological failure in HCV-GT1a-infected patients. There are few data outside clinical trials evaluating their prevalence and impact of elbasvir/grazoprevir. A multicenter...

Descripción completa

Detalles Bibliográficos
Autores principales: Palladino, Claudia, Sánchez-Carrillo, Marta, Mate-Cano, Irene, Vázquez-Morón, Sonia, Jimenez-Sousa, Ma Ángeles, Gutiérrez-Rivas, Mónica, Resino, Salvador, Briz, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460287/
https://www.ncbi.nlm.nih.gov/pubmed/28588311
http://dx.doi.org/10.1038/s41598-017-02968-7