Multiplex gene regulation by CRISPR-ddCpf1

The clustered regularly interspaced short palindromic repeats (CRISPR)/dCas9 system has been widely applied in both transcriptional regulation and epigenetic studies. However, for multiple targets, independent expression of multiple single guide RNAs (sgRNAs) is needed, which is less convenient. To...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaochun, Wang, Jingman, Cheng, Qiuxiang, Zheng, Xuan, Zhao, Guoping, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460296/
https://www.ncbi.nlm.nih.gov/pubmed/28607761
http://dx.doi.org/10.1038/celldisc.2017.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460296/
https://www.ncbi.nlm.nih.gov/pubmed/28607761
http://dx.doi.org/10.1038/celldisc.2017.18

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