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Clinical and genetic factors associated with kidney tubular dysfunction in a real-life single centre cohort of HIV-positive patients
BACKGROUND: Tenofovir (TDF) is one of the most widely used antiretroviral drug. Despite the high degree of tolerability a small percentage of patients experienced alteration in tubular function during TDF use. Intracellular TDF disposition is regulated by ATP-binding cassette (ABC) drug efflux trans...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460416/ https://www.ncbi.nlm.nih.gov/pubmed/28583112 http://dx.doi.org/10.1186/s12879-017-2497-3 |