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Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system

BACKGROUND: Increasing evidence supports a key role for inflammation in the neurodegenerative process of familial amyloidotic polyneuropathy (FAP). While there seems to be an overactivation of the neuronal interleukin-1 signaling pathway, the immune response is apparently compromised in FAP. Accordi...

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Detalles Bibliográficos
Autores principales: Gonçalves, Nádia Pereira, Moreira, João, Martins, Diana, Vieira, Paulo, Obici, Laura, Merlini, Giampaolo, Saraiva, Margarida, Saraiva, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460450/
https://www.ncbi.nlm.nih.gov/pubmed/28583160
http://dx.doi.org/10.1186/s12974-017-0891-9