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miR199a-3p regulates P53 by targeting CABLES1 in mouse cardiac c-kit(+) cells to promote proliferation and inhibit apoptosis through a negative feedback loop

BACKGROUND: MicroRNAs (miRNAs) have emerged as crucial factors that regulate proliferation and apoptosis of cardiac c-kit(+) cells. Although much is known about their role in maintaining cardiac c-kit(+) cell pluripotency, the mechanisms by which they affect cell fate decisions that are an essential...

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Detalles Bibliográficos
Autores principales: Liu, Jingjin, Wang, Yongshun, Cui, Jinjin, Sun, Meng, Pu, Zhongyue, Wang, Chao, Du, Wenjuan, Liu, Xinxin, Wu, Jian, Hou, Jingbo, Zhang, Shuo, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460483/
https://www.ncbi.nlm.nih.gov/pubmed/28583208
http://dx.doi.org/10.1186/s13287-017-0515-4