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HIV drug resistance against strand transfer integrase inhibitors

Integrase strand transfer inhibitors (INSTIs) are the newest class of antiretroviral drugs to be approved for treatment and act by inhibiting the essential HIV protein integrase from inserting the viral DNA genome into the host cell’s chromatin. Three drugs of this class are currently approved for u...

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Detalles Bibliográficos
Autores principales: Anstett, Kaitlin, Brenner, Bluma, Mesplede, Thibault, Wainberg, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460515/
https://www.ncbi.nlm.nih.gov/pubmed/28583191
http://dx.doi.org/10.1186/s12977-017-0360-7